KPV
Anti-inflammatory peptide supporting rapid tissue healing.
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Compound
KPV
Form
Lyophilized Powder
Purity
>99%
Storage
-20°C
Science
Mechanism of Action
KPV is a tripeptide (Lysine-Proline-Valine) derived from the C-terminal of alpha-MSH. It exhibits potent anti-inflammatory properties by inhibiting NF-kB and inflammatory cytokine pathways (IL-1, IL-6, TNF-alpha). Unlike alpha-MSH, KPV provides anti-inflammatory benefits without melanogenic effects, making it a targeted therapeutic for inflammatory conditions.
Benefits
Research Benefits
- Potent anti-inflammatory effects (NF-kB inhibition)
- Reduces pro-inflammatory cytokines (IL-1, IL-6, TNF-α)
- Effective in inflammatory bowel disease (IBD) research
- Promotes wound healing and tissue repair
- No melanogenic side effects (unlike alpha-MSH)
- Oral bioavailability demonstrated in research
Research
Dosage Protocol
Research protocols typically use 250-500mcg daily via subcutaneous injection, or 1-2mg oral administration. Often studied in 4-8 week cycles for inflammatory conditions.
Technical Specifications
Research Comparison
Compare Specs Side-by-Side
| Peptide | ||
|---|---|---|
| Aliases | Lysine-Proline-Valine | |
| CAS Number | 87761-24-4 | |
| Molecular Weight | 329.44 g/mol | |
| Sequence | Lys-Pro-Val | |
| Purity | >99% (HPLC) | |
| Form | Lyophilized Powder | |
| Storage | -20°C | |
| Price | £30 | |
| Mechanism | KPV is a tripeptide (Lysine-Proline-Valine) derived from the C-terminal of alpha-MSH. It exhibits potent anti-inflammatory properties by inhibiting NF-kB and inflammatory cytokine pathways (IL-1, IL-6, TNF-alpha). Unlike alpha-MSH, KPV provides anti-inflammatory benefits without melanogenic effects, making it a targeted therapeutic for inflammatory conditions. | |
| Dosage Protocol | Research protocols typically use 250-500mcg daily via subcutaneous injection, or 1-2mg oral administration. Often studied in 4-8 week cycles for inflammatory conditions. |
Comparison for research purposes only · All peptides >99% HPLC-verified purity
Stability
Storage Guidelines
Store lyophilized powder at -20°C. Reconstituted solution stable at 2-8°C for up to 30 days. Protect from light.
Safety
Safety & Effects
KPV has demonstrated excellent safety in preclinical studies. No significant adverse effects reported at therapeutic doses. No melanogenic or hormonal effects observed.
Scientific Literature
Published Research
Journal of Immunology, 2009
KPV Anti-inflammatory Mechanism
Inhibits NF-kB and pro-inflammatory cytokines
PubMed →Annals of the New York Academy of Sciences, 2003
Alpha-MSH C-terminal Peptide KPV
Potent anti-inflammatory without melanogenic effects
PubMed →Gut, 2014
KPV in Inflammatory Bowel Disease
Reduces intestinal inflammation in colitis models
PubMed →Research Tool
Peptide Reconstitution Calculator
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Visual Reconstitution Calculator
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Units to Draw
20 U
Volume
0.200 ml
Concentration
50 mcg/U
Total Doses
10
Research use only · Not for human consumption
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